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Abstract: The metabolism of Δ 9-tetrahydrocannabinol (THC) and related cannabinoids in man has been studied in detail utilizing intravenous, oral, and smoking routes of administration.The general pattern of metabolism was the same in all studies involving THC and related cannabinoids. Microsomal hydroxylation allylic to the Δ 9-THC double bond occurs, the major product resulting in formation ...
They used a line with 11 identical boxes, where the extremes represented the pain limitation of patients, from absent to severe, respectively. At 6, 12, and 24 h after the LTMI, patients were instructed to mark an X in the box on the scale to indicate their pain intensity. ... New York: Raven Press; 1983. pp. 33-37. [Google Scholar] 40. Silva ...
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